Nowadays, we are going a step forward into the new era for the sustainable production of industrial commodity products such as energy, fine-chemicals, active compounds and materials from renewable biomass. Diatoms (Bacillariophyta) are the most abundant species of phytoplankton on this earth and play vital roles as primary producers on this planet1. Diatoms regulate an expression of Fucoxanthin chlorophyll a/c-binding proteins (FCPs) with the pigment contents in response to light. As a photosynthetic microorganism, they contain pigments, which have a high market value in the cosmetic, pharmaceutical and food colorant industries and function as aquatic living feed because they contain bioactive and nutritious compounds such as eicosapentaenoic acid (EPA) and fucoxanthin (Fx). New methods will be applied for the growth of diatoms under low and high intensity of white, blue, green and red LEDs illumination and the study that will emerge out of this project will add important knowledge to fundamental and applied research. The use of glutamic acid in the chlorophyll a/c biosynthesis in conjunction with 15N, 18O2, 13C, and D2O isotopes will be our new approach for metabolism studies of fatty acids and carotenoids by using uniformly labeled 13C fatty acids and for extensive full spectroscopic characterization of all pigments in the marine cells.